The Safe Brain Initiative translates validated science into bedside practice — protecting patients from postoperative delirium, cognitive dysfunction, and avoidable neurological harm.
SBI addresses three distinct stakeholders. Choose your role to access content calibrated for your specific clinical, economic, or personal context.
Anaesthesiologists, intensivists, and perioperative nurses seeking evidence-based tools to implement neuroprotection at the bedside.
CFOs and CMOs evaluating the return on investment of perioperative brain health programmes under Value-Based Healthcare frameworks.
Individuals preparing for surgery who want to ask the right questions and understand their right to neuroprotective care.
Four interconnected pillars from foundational physiology to real-world implementation, each supported by peer-reviewed evidence.
Physiological rationale for why surgical anaesthesia creates a window of neurological risk — independent of pre-existing pathology.
Patient-Centred Precision Care: a structured methodology linking intraoperative monitoring with postoperative functional outcomes.
Multicentre real-world data validating the 18-point bundle across surgical specialties, geographies, and patient risk profiles.
Practical protocols, SOPs, and learning system architecture ensuring the 0.96 OR/month improvement compounds over time.
The SBI Clinician Spoke provides the competency pathway, tools, and peer network to move from published data to clinical habit — one operating room at a time.
Pulse oximetry became a universal standard based on physiological rationale, not mortality trials. The 1993 Møller study of 20,802 patients showed a 19-fold increase in hypoxemia detection without a mortality benefit — and yet no one questions its use today. Brain monitoring meets the same threshold.
Compound delirium risk reduction with sustained bundle use
Every month without a neuroprotection programme is a month of preventable delirium cases, extended ICU stays, and unnecessary readmissions billed to your institution.
The SBI framework reframes anaesthesia from an event to a service — where outcomes, not processes, determine value. Under the Value-Based Healthcare Equation (Value = Outcomes / Cost), perioperative brain health is a financial instrument, not merely a clinical preference.
Attributed to postoperative delirium complications
Per patient per year (Gou et al., 2021)
Identifiable waste streams eliminated by bundle implementation
Reduced ICU days and medication waste improve sustainability scoring
Estimate your institution's annual cost of inaction.
Based on $44,291/case (Gou et al., 2021). Model for estimation purposes only.
Surviving surgery is the baseline, not the goal. The goal is returning to the life you had — with your memory, your personality, and your independence intact.
Postoperative delirium and cognitive dysfunction are not inevitable. They are largely preventable, and you can advocate for the monitoring and care bundle that reduces your risk. Ask your anaesthetist a direct question before you go to theatre.
The checklist on the right is yours to print and bring to your pre-operative assessment. You are entitled to shared decision-making. This is what it looks like in practice.
Neuroprotection requires both a process measure and an outcome measure. One without the other is incomplete science.
Real-time guidance. Burst suppression detection. Titration of anaesthetic depth. The GPS of neuroprotection.
QoR-15 and WHODAS 2.0 verify cognitive and functional return to baseline — closing the evidence loop.
Mini-Cog + ASA status calculator to determine bundle intensity for each patient.
Real-time benchmarking against global SBI network averages. GDPR-compliant, EU-hosted.
A growing network of clinicians, institutions, and champions committed to making neuroprotective care the perioperative default.
Narrative infrastructure and digital architecture.
Content scaling and first training pilots.
Institutional partnerships and journal submissions.
Global data integration and Year 1 reporting.
| Metric | Month 3 | Month 6 | Month 12 |
|---|---|---|---|
| Web visitors / month | 2,000 | 5,000 | 15,000 |
| LinkedIn followers | 1,500 | 5,000 | 10,000 |
| Trained Champions | 60 | 200 | 500 |
Just as H. pylori's discovery took a decade to change gastric ulcer practice at the cost of 500,000 unnecessary surgeries, perioperative medicine faces the same choice today: inertia or implementation.