Safe Brain Initiative
PROs & POD Matter
Adverse Patient Reported Outcomes and Postoperative Delirium are not only uncomfortable and dangerous but also costly on an individual and societal level.
Why it matters
Adverse Patient Reported Outcomes and Postoperative Delirium — reasons to make a change
Patients experience an unnecessarily high level of side effects associated with their anaesthesia and surgical treatment. These include nausea, severe pain, anxiety, stress, reduced general well-being and others. Furthermore, many patients develop cerebral dysfunctions postoperatively, such as Postoperative Delirium (POD). POD is a severe complication with an incidence rate of up to 50% starting in the recovery room. It is associated with several deleterious clinical consequences such as short- and long-term cognitive morbidity, increased short- and long-term mortality, reduced quality of life and tremendous in-hospital and out-of-hospital costs.
However, clinicians and administrative staff are not provided systematic feedback on basic patient-reported outcomes (PROs) and cerebral complications such as postoperative delirium (POD). As a result, the very basic cause-and-effect learning necessary to reduce such side effects is lacking. Furthermore, this created a significant barrier to recognising the need and value of patient-centred precision care, quality improvement, and value-based healthcare in general.
Using a systematic approach, the Safe Brain Initiative will help to collect and analyse real-world healthcare outcomes data to monitor, visualise, and improve essential preventive routine care and patient-reported outcomes. This initiative aims to strengthen the perioperative healthcare system while concentrating on three focused areas.
From data to improved outcome
As dedicated clinicians, we strive to improve our patient outcomes in all aspects. The Safe Brain Initiative and our case report form (e- & p-CRF) give the clinician a systematic and easy-to-use tool to monitor and record changes.

Recommendations
The SBI Program
The Safe Brain Initiative Program
Education
The Masterclass programme
A central part of the Safe Brain Initiative is sharing the current knowledge and results of our research. Feel free to join our different events — from masterclasses and podcasts to bootcamps.
Sources
- Eur J Anaesthesiology. 2017 Apr;34(4):192–214. doi: 10.1097/EJA
- Crit Care Med. 2018 Sep;46(9):e825–e873
- Ger Med Sci. 2015;13:Doc19
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